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Papers for Prof. Andrew Sharott

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2026

Unit Paper
Duchet B
Subramaniam S
Greenway A
He S
Shackle N
Pogosyan A
Denison T
Sharott A
Tan H
Bogacz R

Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans.

2026. Brain Stimul, 19(3):103111.

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PMC13328066
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3.29 MB
Unit Paper
Myatt J
Toth R
Denison T
Grennan I
McNamara CG
Stagg CJ
Sharott A

Modulation of motor cortical theta and gamma oscillations using phase-targeted, closed-loop optogenetic stimulation of local excitatory and inhibitory neurons.

2026. Brain Stimul, 19(2):103034.

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5.43 MB

2025

Unit Paper
Härmson O
Grennan I
Perry B
Toth R
McNamara CG
Denison T
Cagnan H
Manohar S
Walton ME
Sharott A

Multi-level encoding of reward, effort, and choice across the frontal cortex and basal ganglia during cost-benefit decision-making.

2025. Cell Rep, 44(2):115209.

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PMC11860760
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2.96 MB
Unit Paper
Mirkhani N
McNamara CG
Oliviers G
Sharott A
Duchet B
Bogacz R

Response of Neuronal Populations to Phase-Locked Stimulation: Model-Based Predictions and Validation.

2025. J Neurosci, 45(15):e2269242025
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PMC11984083
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3.55 MB

2024

Unit Paper
Clarke-Williams CJ
Lopes-Dos-Santos V
Lefèvre L
Brizee D
Causse AA
Rothaermel R
Hartwich K
Perestenko PV
Toth R
McNamara CG
Sharott A
Dupret D

Coordinating brain-distributed network activities in memory resistant to extinction.

2024. Cell, 187(2):409-427.
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PMC7615560
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8.24 MB
Unit Paper
van Rheede JJ
Alagapan S
Denison T
Riva-Posse P
Rozell CJ
Mayberg HS
Waters AC
Sharott A

Cortical signatures of sleep are altered following effective deep brain stimulation for depression.

2024. Transl Psychiatry, 14(1):103.

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PMC10879134
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2.86 MB
Unit Paper
Gava GP
Lefèvre L
Broadbelt T
McHugh SB
Lopes-Dos-Santos V
Brizee D
Hartwich K
Sjoberg H
Perestenko PV
Toth R
Sharott A
Dupret D

Organizing the coactivity structure of the hippocampus from robust to flexible memory.

2024. Science, 385(6713):1120-1127.

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PMC7616439
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13.68 MB
Unit Paper
McHugh SB
Lopes-Dos-Santos V
Castelli M
Gava GP
Thompson SE
Tam SKE
Hartwich K
Perry B
Toth R
Denison T
Sharott A
Dupret D

Offline hippocampal reactivation during dentate spikes supports flexible memory.

2024. Neuron, 112(22):3768-3781.e8.

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PMC7616703
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12.57 MB
Unit Paper
Grennan I
Mallet N
Magill PJ
Cagnan H
Sharott A

Beta bursts in the parkinsonian cortico-basal ganglia network form spatially discrete ensembles.

2024. Neurobiol Dis, 201:106652.

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PMC11496931
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9.4 MB
Unit Paper
van Rheede JJ
Alagapan S
Denison T
Riva-Posse P
Rozell CJ
Mayberg HS
Waters AC
Sharott A

Cortical signatures of sleep are altered following effective deep brain stimulation for depression

2024. Translational Psychiatry, 14(1), 103.
Full Text PDF
2.86 MB

2023

Unit Paper
Wiest C
Torrecillos F
Pogosyan A
Bange M
Muthuraman M
Groppa S
Hulse N
Hasegawa H
Ashkan K
Baig F
Morgante F
Pereira EA
Mallet N
Magill PJ
Brown P
Sharott A
Tan H

The aperiodic exponent of subthalamic field potentials reflects excitation/inhibition balance in Parkinsonism.

2023. eLife, 12:e82467

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PMC10005762
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1.17 MB

2022

Unit Paper
West TO
Magill PJ
Sharott A
Litvak V
Farmer SF
Cagnan H

Stimulating at the right time to recover network states in a model of the cortico-basal ganglia-thalamic circuit.

2022. PLoS Comput Biol, 18(3)e1009887.

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PMC8939795
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3.33 MB
Peng Y
Schöneberg N
Esposito MS
Geiger JRP
Sharott A
Tovote P

Current approaches to characterize micro- and macroscale circuit mechanisms of Parkinson's disease in rodent models.

2022. Exp Neurol, 351:114008.

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PMC7612860
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3.72 MB
Unit Paper
van Rheede JJ
Feldmann LK
Busch JL
Fleming JE
Mathiopoulou V
Denison T
Sharott A
Kühn AA

Diurnal modulation of subthalamic beta oscillatory power in Parkinson's disease patients during deep brain stimulation.

2022. NPJ Parkinsons Dis, 8(1):88.
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PMC9270436
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23.06 MB
Unit Paper
McNamara CG
Rothwell M
Sharott A

Stable, interactive modulation of neuronal oscillations produced through brain-machine equilibrium.

2022. Cell Rep, 41(6):111616.
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PMC7614081
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2.32 MB

2021

Unit Paper
Nakamura KC
Sharott A
Tanaka T
Magill PJ

Input Zone-Selective Dysrhythmia in Motor Thalamus after Dopamine Depletion.

2021. J Neurosci, 41(50):10382-10404.
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PMC8672689
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8.6 MB

2020

Unit Paper
Baaske MK
Kormann E
Holt AB
Gulberti A
McNamara CG
Pötter-Nerger M
Westphal M
Engel AK
Hamel W
Brown P
Moll CK
Sharott A

Parkinson's disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input in vivo.

2020. Neurobiol. Dis., 146:105119.
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PMC7710979
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7.35 MB
Unit Paper
McNamara CG
Sharott A

Patent Granted: Apparatus and method for phase tracking an oscillatory signal

2020. WO/2020/183152
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1.95 MB

2019

Unit Paper
Holt AB
Kormann E
Gulberti A
Pötter-Nerger M
McNamara CG
Cagnan H
Baaske MK
Little S
Köppen JA
Buhmann C
Westphal M
Gerloff C
Engel AK
Brown P
Hamel W
Moll CK
Sharott A

Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients.

2019. J. Neurosci., 39(6):1119-1134.
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PMC6363933
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3.34 MB
Unit Paper
Trouche S
Koren V
Doig NM
Ellender TJ
El-Gaby M
Lopes-Dos-Santos V
Reeve HM
Perestenko PV
Garas FN
Magill PJ
Sharott A
Dupret D

A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.

2019. Cell, 176(6):1393-1406.e16.

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PMC6424821
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9.58 MB
Unit Paper
Meidahl AC
Moll CK
van Wijk B
Gulberti A
Tinkhauser G
Westphal M
Engel AK
Hamel W
Brown P
Sharott A

Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients.

2019. Neurobiol. Dis., 127:101-113.
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PMC6545172
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2.71 MB
Unit Paper
Reis C
Sharott A
Magill PJ
van Wijk B
Parr T
Zeidman P
Friston KJ
Cagnan H

Thalamocortical dynamics underlying spontaneous transitions in beta power in Parkinsonism.

2019. Neuroimage, 193:103-114.
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PMC6503152
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1.35 MB
Unit Paper
Cagnan H
Mallet N
Moll CK
Gulberti A
Holt AB
Westphal M
Gerloff C
Engel AK
Hamel W
Magill PJ
Brown P
Sharott A

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network.

2019. Proc. Natl. Acad. Sci. U.S.A., 116:16095-16104.
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PMC6690030
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1.59 MB

2018

Unit Paper
Garas FN
Kormann E
Shah RS
Vinciati F
Smith Y
Magill PJ
Sharott A

Structural and molecular heterogeneity of calretinin-expressing interneurons in the rodent and primate striatum.

2018. J. Comp. Neurol., 526(5):877-898.
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PMC5814860
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2.44 MB
Unit Paper
West TO
Berthouze L
Halliday DM
Litvak V
Sharott A
Magill PJ
Farmer SF

Propagation of beta/gamma rhythms in the cortico-basal ganglia circuits of the parkinsonian rat.

2018. J. Neurophysiol., 119(5):1608-1628.
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PMC6008089
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5.47 MB
Unit Paper
Sharott A
Gulberti A
Hamel W
Köppen JA
Münchau A
Buhmann C
Pötter-Nerger M
Westphal M
Gerloff C
Moll CK
Engel AK

Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease.

2018. Neurobiol. Dis., 112:49-62.
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PMC5821899
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1.92 MB

2017

Unit Paper
Sharott A
Vinciati F
Nakamura KC
Magill PJ

A Population of Indirect Pathway Striatal Projection Neurons Is Selectively Entrained to Parkinsonian Beta Oscillations.

2017. J. Neurosci., 37(41):9977-9998.
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PMC5637121
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4.33 MB

2016

Unit Paper
Garas FN
Shah RS
Kormann E
Doig NM
Vinciati F
Nakamura KC
Dorst MC
Smith Y
Magill PJ
Sharott A

Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons.

2016. eLife, 5:e16088.
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PMC5036963
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6.62 MB

2015

Unit Paper
Abdi A
Mallet N
Mohamed FY
Sharott A
Dodson PD
Nakamura KC
Suri S
Avery SV
Larvin JT
Garas FN
Garas SN
Vinciati F
Morin S
Bezard E
Baufreton J
Magill PJ

Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus.

2015. J. Neurosci., 35(17):6667-88.
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PMC4412890
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5.48 MB

2014

Doig NM
Magill PJ
Apicella P
Bolam JP
Sharott A

Cortical and thalamic excitation mediate the multiphasic responses of striatal cholinergic interneurons to motivationally salient stimuli.

2014. J. Neurosci., 34(8):3101-17.
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PMC3931511
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4.31 MB
Sharott A
Gulberti A
Zittel S
Tudor Jones AA
Fickel U
Münchau A
Köppen JA
Gerloff C
Westphal M
Buhmann C
Hamel W
Engel AK
Moll CK

Activity parameters of subthalamic nucleus neurons selectively predict motor symptom severity in Parkinson's disease.

2014.J. Neurosci., 34(18):6273-85.

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PMC4004813
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2.1 MB
von Nicolai C
Engler G
Sharott A
Engel AK
Moll CK
Siegel M

Corticostriatal coordination through coherent phase-amplitude coupling.

2014.J. Neurosci., 34(17):5938-48.

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595.69 KB
Moll CK
Galindo-Leon E
Sharott A
Gulberti A
Buhmann C
Koeppen JA
Biermann M
Bäumer T
Zittel S
Westphal M
Gerloff C
Hamel W
Münchau A
Engel AK

Asymmetric pallidal neuronal activity in patients with cervical dystonia.

2014.Front Syst Neurosci, 8():15.

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PMC3920073
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2.3 MB
Nakamura KC
Sharott A
Magill PJ

Temporal coupling with cortex distinguishes spontaneous neuronal activities in identified basal ganglia-recipient and cerebellar-recipient zones of the motor thalamus.

2014.Cereb. Cortex, 24(1):81-97.

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PMC3862266
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14.83 MB
Brittain JS
Sharott A
Brown P

The highs and lows of beta activity in cortico-basal ganglia loops.

2014.Eur. J. Neurosci., 39(11):1951-9.

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PMC4285950
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699.93 KB

2013

Grieb B
von Nicolai C
Engler G
Sharott A
Papageorgiou I
Hamel W
Engel AK
Moll CK

Decomposition of abnormal free locomotor behavior in a rat model of Parkinson's disease.

2013.Front Syst Neurosci, 7():95.

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PMC3842038
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1.69 MB

2012

Sharott A
Doig NM
Mallet N
Magill PJ

Relationships between the firing of identified striatal interneurons and spontaneous and driven cortical activities in vivo.

2012. J. Neurosci., 32(38):13221-36.
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PMC4242971
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3.63 MB

2011

Syed EC
Sharott A
Moll CK
Engel AK
Kral A

Effect of sensory stimulation in rat barrel cortex, dorsolateral striatum and on corticostriatal functional connectivity.

2011.Eur. J. Neurosci., 33(3):461-70.

2009

Sharott A
Moll CK
Engler G
Denker M
Grün S
Engel AK

Different subtypes of striatal neurons are selectively modulated by cortical oscillations.

2009.J. Neurosci., 29(14):4571-85.

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2.1 MB
Salih F
Sharott A
Khatami R
Trottenberg T
Schneider G
Kupsch A
Brown P
Grosse P

Functional connectivity between motor cortex and globus pallidus in human non-REM sleep.

2009.J. Physiol. (Lond.), 587(Pt 5):1071-86.

Free Full Text at Europe PMC
PMC2673776
Moll CK
Sharott A
Hamel W
Münchau A
Buhmann C
Hidding U
Zittel S
Westphal M
Müller D
Engel AK

Waking up the brain: a case study of stimulation-induced wakeful unawareness during anaesthesia.

2009.Prog. Brain Res., 177():125-45.

2008

Mallet N
Pogosyan A
Sharott A
Csicsvari J
Bolam JP
Brown P
Magill PJ

Disrupted dopamine transmission and the emergence of exaggerated beta oscillations in subthalamic nucleus and cerebral cortex.

2008.J. Neurosci., 28(18):4795-806.

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1.13 MB
Sharott A
Grosse P
Kühn AA
Salih F
Engel AK
Kupsch A
Schneider GH
Krauss JK
Brown P

Is the synchronization between pallidal and muscle activity in primary dystonia due to peripheral afferance or a motor drive?

2008.Brain, 131(Pt 2):473-84.

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444.47 KB
Lalo E
Thobois S
Sharott A
Polo G
Mertens P
Pogosyan A
Brown P

Patterns of bidirectional communication between cortex and basal ganglia during movement in patients with Parkinson disease.

2008.J. Neurosci., 28(12):3008-16.

2006

Magill PJ
Pogosyan A
Sharott A
Csicsvari J
Bolam JP
Brown P

Changes in functional connectivity within the rat striatopallidal axis during global brain activation in vivo.

2006.J. Neurosci., 26(23):6318-29.

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2.14 MB
Magill PJ
Sharott A
Bolam JP
Brown P

Delayed synchronization of activity in cortex and subthalamic nucleus following cortical stimulation in the rat.

2006.J. Physiol. (Lond.), 574(Pt 3):929-46.

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PMC1817747
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629.61 KB

2005

Sharott A
Magill PJ
Bolam JP
Brown P

Directional analysis of coherent oscillatory field potentials in the cerebral cortex and basal ganglia of the rat.

2005.J. Physiol. (Lond.), 562(Pt 3):951-63.

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PMC1665537
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850.89 KB
Sharott A
Magill PJ
Harnack D
Kupsch A
Meissner W
Brown P

Dopamine depletion increases the power and coherence of beta-oscillations in the cerebral cortex and subthalamic nucleus of the awake rat.

2005.Eur. J. Neurosci., 21(5):1413-22.

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473.69 KB
Magill PJ
Sharott A
Harnack D
Kupsch A
Meissner W
Brown P

Coherent spike-wave oscillations in the cortex and subthalamic nucleus of the freely moving rat.

2005.Neuroscience, 132(3):659-64.

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388.91 KB

2004

Magill PJ
Sharott A
Bevan MD
Brown P
Bolam JP

Synchronous unit activity and local field potentials evoked in the subthalamic nucleus by cortical stimulation.

2004.J. Neurophysiol., 92(2):700-14.

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918.8 KB
Magill PJ
Sharott A
Bolam JP
Brown P

Brain state-dependency of coherent oscillatory activity in the cerebral cortex and basal ganglia of the rat.

2004.J. Neurophysiol., 92(4):2122-36.

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1.35 MB
Fisher RJ
Sharott A
Kühn AA
Brown P

Effects of combined cortical and acoustic stimuli on muscle activity.

2004.Exp Brain Res, 157(1):1-9.

Kühn AA
Sharott A
Trottenberg T
Kupsch A
Brown P

Motor cortex inhibition induced by acoustic stimulation.

2004.Exp Brain Res, 158(1):120-4.

2003

Sharott A
Marsden J
Brown P

Primary orthostatic tremor is an exaggeration of a physiological response to instability.

2003.Mov. Disord., 18(2):195-9.

Moss S
Sharott A
Goodhead LH
Mitchell SN

Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.

2003.Eur. J. Pharmacol., 460(2-3):117-25.

2002

Brown P
Kupsch A
Magill PJ
Sharott A
Harnack D
Meissner W

Oscillatory local field potentials recorded from the subthalamic nucleus of the alert rat.

2002.Exp. Neurol., 177(2):581-5.

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154.08 KB